Chinese oral COVID-19 drug effective against Omicron

Scientists have found that China’s oral COVID-19 nucleoside drug VV116 can shorten viral shedding time in patients infected with the Omicron variant of the virus by two to three days.

The researchers from Fudan University conducted an open, prospective cohort study to evaluate the safety and effectiveness of VV116 in 136 patients hospitalized with the Omicron variant from March 8 to 24.

Among the participants who received standard treatment, 60 patients received VV116, and 76 patients did not, according to the study published on Wednesday in the journal Emerging Microbes & Infections.

The researchers found that those in the treatment group, who received VV116 within five days of their first positive test, had an average viral shedding time of 8.56 days, while those in the control group had an average time of 11.13 days, according to the study .A medic takes a swab sample from a resident for nucleic acid test at a community in Haidian District of Beijing, capital of China, May 13, 2022. Beijing has started three additional rounds of mass nucleic acid testing in 12 districts from Friday to Sunday, as the Chinese capital races against time to contain the latest resurgence of COVID-19 infections

It also reported a total of nine mild adverse events in the VV116 group, seven of which were mild liver function abnormalities. All events were resolved without intervention. VV116 is a safe, effective oral antiviral drug, showing an improved performance during the early onset of Omicron infection, the researchers said.

VV116 has commenced global trials in moderate and severe COVID-19 patients after it was proven to be safe and well-tolerated in tests involving healthy people. Its developers include several institutes under the Chinese Academy of Sciences, as well as Shanghai Junshi Biosciences Co., Ltd. and Suzhou-based Vigonvita Life Sciences Co., Ltd

Source: This news is originally published by cgtn