Flu Vaccination Linked to 40% Lower Risk of Alzheimer’s Disease

A new study finds that flu vaccination was associated with a 40% reduced risk for Alzheimer’s disease over a four-year period.

Flu Vaccination Linked to 40% Lower Risk of Alzheimer’s Disease

Over the course of four years, those who received at least one influenza vaccine were 40% less likely than their non-vaccinated peers to acquire Alzheimer’s disease, according to a new study from the University of Texas Health Science Center at Houston. Researchers compared the risk of Alzheimer’s disease incidence between patients with and without prior flu vaccination in a large nationwide sample of U.S. adults aged 65 and older. The study was led by first author Avram S. Bukhbinder, MD, a recent alumnus of McGovern Medical School at UTHealth Houston, and senior author Paul. E. Schulz, MD, the Rick McCord Professor in Neurology at McGovern Medical School. An early online version of the paper detailing the findings is available in advance of its publication in the August 2, 2022, issue of the Journal of Alzheimer’s Disease.

We found that flu vaccination in older adults reduces the risk of developing Alzheimer’s disease for several years. The strength of this protective effect increased with the number of years that a person received an annual flu vaccine – in other words, the rate of developing Alzheimer’s was lowest among those who consistently received the flu vaccine every year,” said Bukhbinder, who is still part of Schulz’s research team while in his first year of residency with the Division of Child Neurology at Massachusetts General Hospital. “Future research should assess whether flu vaccination is also associated with the rate of symptom progression in patients who already have Alzheimer’s dementia.”

The research study which comes two years after UTHealth Houston researchers found a possible link between the flu vaccine and reduced risk of Alzheimer’s disease – analyzed a much larger sample than previous research, including 935,887 flu-vaccinated patients and 935,887 non-vaccinated patients. During four-year follow-up appointments, about 5.1% of flu-vaccinated patients were found to have developed Alzheimer’s disease. Meanwhile, 8.5% of non-vaccinated patients had developed Alzheimer’s disease during follow-up. These results underscore the strong protective effect of the flu vaccine against Alzheimer’s disease, according to Bukhbinder and Schulz. However, the underlying mechanisms behind this process require further study.

Source: This news is originally published by scitechdaily